Research into using pig organs for human transplants is moving quickly as a solution to the serious shortage of organs. At a research center in the Blue Ridge mountains, pigs are genetically modified and raised with strict safety rules to prevent infections. Revivicor Inc., a biotech company, has created these “designer pigs” with special genetic changes, making their organs more likely to be accepted by humans. In the U.S., the first pig-to-human transplants used hearts and kidneys from these modified pigs. Although the patients did not survive long, these early tests gave scientists important data to improve the process. Now, researchers are studying baboons and human bodies to gather more information and get FDA approval for larger trials. To create these pigs, scientists use advanced gene editing to remove pig genes that could cause problems for humans and add human genes to lower the chance of organ rejection. At United Therapeutics’ $75 million facility, pigs are raised in clean conditions with special filters and safety measures. If trials succeed, experts believe these facilities could one day produce thousands of pig organs yearly, offering a new way to meet the growing need for transplants.