Three genetically modified wolf puppies, designed to resemble the extinct dire wolf, have been born and are currently being observed in a secure facility in the United States, according to biotechnology company Colossal Biosciences. These young wolves, aged between three to six months, already weigh around 80 pounds and are expected to grow to 140 pounds. Dire wolves, which disappeared over 10,000 years ago, were significantly larger than today’s gray wolves. Using ancient DNA from fossil remains found in Ohio and Idaho, researchers identified key physical characteristics of the dire wolf. With the help of CRISPR gene-editing technology, scientists modified 20 specific parts of gray wolf DNA and created embryos with these changes. These embryos were implanted into domestic dog surrogates, resulting in the birth of the genetically engineered puppies.

This breakthrough illustrates how advanced biotechnology is being used to revive traits of extinct species, although experts clarified that creating a complete replica of a dire wolf remains improbable. Professor Vincent Lynch from the University at Buffalo stated that current methods only allow for superficial similarities, not full restoration. Colossal has also announced the cloning of four red wolves to support genetic diversity in endangered populations. Wildlife specialists noted that the cloning process used was less invasive than traditional methods. However, procedures such as sedating wild wolves for blood samples still pose challenges. Despite debates surrounding ecological limitations, the U.S. Interior Department acknowledged the project as a remarkable achievement in the scientific field. The endeavor may have future implications for conservation and genetic restoration efforts worldwide.