The International Space Station (ISS) marked its 25th year of human stay in space in early November 2025. Since November 2, 2000, astronauts from many countries have lived and worked in the station that moves around Earth about 400 kilometers above the ground. The first crew included Bill Shepherd from NASA and Sergei Krikalev and Yuri Gidzenko from Russia. The ISS has welcomed more than 290 people from 26 nations. This long mission is a remarkable and monumental sign of teamwork and resilience in science and technology, showing the value of global cooperation.

Research in the ISS has been pivotal in learning how living things and objects react to space. Studies on plants, health, and materials help scientists understand life in microgravity. A twin study by NASA gave insightful results about the body’s changes in space. Even with challenges like broken tools and space debris, the ISS continues to serve as a legacy of sustainable advancement and human exploration beyond Earth.